C. rodentium-induced colitis
Jiang et al. (2016) established the C. rodentium -induced colitis
model approach [15] that was used the
present study. The mice in the CR and TS+CR groups were rapidly
administered 2×109 CFU/mL C. rodentium 24 h
after fasting, while the mice in the control and TS groups were
administered the same amount of PBS. The colitis mouse model elicited a
Th1-type immune response, which was similar to that observed in human
CD. Inflammation was assessed based on bellowed parameters, including
clinical disease activity and the macroscopic and microscopic
inflammation scores in the colon tissue. The grading was performed by
three investigators blinded for the treatment of the mice.