Efficacy evaluation
Efficacy evaluations at week 6, 12, 33 and 52 were performed using the IGA scale (Table II and III). IGA assessment throughout the trial was performed as open-end analysis by the treating physician. Furthermore, patients rated their satisfaction according to improvement in overall appearance and texture on a 5-point Likert scale (very dissatisfied, dissatisfied, no opinion, satisfied and very satisfied) at the end of the study.