Patients
This trial represents a series of collected cases of patients treated
for moderate to severe inflammatory facial acne. Enrolled patients were
overall ineligible to standard dose of retinoids for health or personal
reasons. A urine or blood pregnancy test was required for female
subjects at the screening, baseline and then every 4 weeks for all the
period of the study. Detailed criteria for inclusion and exclusion are
listed in Table I.
Acne severity was graded according to the Investigator’s Global
Assessment (IGA) scale (Table II) 66-68, by the
treating physician. In total 12 cases were included, seven male and five
female patients. Baseline grading ensured that 50% of the patients
presented with moderate (IGA 3) and 50% with severe (IGA 4) acne (Table
III).