Figure 1. FLE treatment combined with low-dose isotretinoin
A) A 28 year old female patient presenting with baseline acne
severity of IGA 4. The patient was not eligible to standard doses of
isotretinoin, due to previous discontinued therapy due to severe dryness
of the skin, and previous tetracycline treatment did not improve the
acne. The patient was started on low-dose isotretinoin and
drospirenone/ethinyl estradiol (OCP) combined with FLE treatment.B) A 27 year old female patient presenting with baseline acne
severity of IGA 4, previously treated with topical treatment and
tetracycline without effect. Due to the patient´s history of pseudotumor
cerebri, the patient was not eligible to start standard doses of
tetracycline or isotretinoin and was started in low-dose isotretinoin
and levonogestrel (IUD) combined with FLE treatment. C) A 18
year old male patient presenting with baseline acne severity of IGA 4.
The patient was previously treated with topical treatment, tetracycline
without effect, and discontinued isotretinoin due to elevated levels of
creatine phosphokinase (CPK), and thereby not eligible to standard dose
of isotretinoin. The patient was started in low-dose isotretinoin
combined with FLE treatment. D) A 20 year old female patient
presenting with baseline acne severity of IGA 4, previously undergoing
topical therapy without effect, now wishing fast response before
summertime. The patient was started in isotretinoin combined with FLE
treatment. Appearance of the skin as presented at each evaluation;
baseline (upper row), week 6 (second row from top), week 12 (third row
from top), week 33 (fourth row from top), and week 52 (bottom row).