Figure 1. FLE treatment combined with low-dose isotretinoin
A) A 28 year old female patient presenting with baseline acne severity of IGA 4. The patient was not eligible to standard doses of isotretinoin, due to previous discontinued therapy due to severe dryness of the skin, and previous tetracycline treatment did not improve the acne. The patient was started on low-dose isotretinoin and drospirenone/ethinyl estradiol (OCP) combined with FLE treatment.B) A 27 year old female patient presenting with baseline acne severity of IGA 4, previously treated with topical treatment and tetracycline without effect. Due to the patient´s history of pseudotumor cerebri, the patient was not eligible to start standard doses of tetracycline or isotretinoin and was started in low-dose isotretinoin and levonogestrel (IUD) combined with FLE treatment. C) A 18 year old male patient presenting with baseline acne severity of IGA 4. The patient was previously treated with topical treatment, tetracycline without effect, and discontinued isotretinoin due to elevated levels of creatine phosphokinase (CPK), and thereby not eligible to standard dose of isotretinoin. The patient was started in low-dose isotretinoin combined with FLE treatment. D) A 20 year old female patient presenting with baseline acne severity of IGA 4, previously undergoing topical therapy without effect, now wishing fast response before summertime. The patient was started in isotretinoin combined with FLE treatment. Appearance of the skin as presented at each evaluation; baseline (upper row), week 6 (second row from top), week 12 (third row from top), week 33 (fourth row from top), and week 52 (bottom row).