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A challenging diagnosis of a non-secretor plasma cell dyscrasia with pleomorphic plasmablastic morphology.
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  • Stijn Van Landeghem,
  • Sara Capiau,
  • Jean-Louis Bayart,
  • Philip Vlummens,
  • Jo Van Dorpe,
  • Nadine Van Roy,
  • Jan Philippé
Stijn Van Landeghem
University Hospital Ghent
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Sara Capiau
University Hospital Ghent
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Jean-Louis Bayart
University Hospital Ghent
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Philip Vlummens
University Hospital Ghent
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Jo Van Dorpe
University Hospital Ghent
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Nadine Van Roy
University Hospital Ghent
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Jan Philippé
University Hospital Ghent
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Peer review status:ACCEPTED

18 Jun 2020Submitted to Clinical Case Reports
24 Jun 2020Assigned to Editor
24 Jun 2020Submission Checks Completed
15 Jul 2020Reviewer(s) Assigned
18 Jul 2020Review(s) Completed, Editorial Evaluation Pending
22 Jul 2020Editorial Decision: Accept

Abstract

Differentiating plasmablastic lymphoma and plasmablastic myeloma is challenging due to overlapping morphological and immunophenotypical features. This case demonstrates the difficulty to distinguish a non-secretor myeloma with plasmablastic morphology from a plasmablastic lymphoma and the necessity of a multidisciplinary approach to make an accurate diagnosis because the treatment protocols are different.