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Optically transparent electrodes to study living cells: a mini review
  • +2
  • Artem Kuzovlev,
  • Anatoly Evseev,
  • Irina Goroncharovskaya,
  • Aslan Shabanov,
  • Sergey Petrikov
Artem Kuzovlev
Federal research and clinical center of intensive care medicine and rehabilitology
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Anatoly Evseev
N V Sklifosovsky Research Institute of Emergency Medicine
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Irina Goroncharovskaya
N V Sklifosovsky Research Institute of Emergency Medicine
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Aslan Shabanov
N V Sklifosovsky Research Institute of Emergency Medicine
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Sergey Petrikov
N V Sklifosovsky Research Institute of Emergency Medicine
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Peer review status:POSTED

24 Jun 2020Submitted to Biotechnology and Bioengineering
25 Jun 2020Assigned to Editor
25 Jun 2020Submission Checks Completed

Abstract

The use of electrochemical methods to study living systems, including cells, has been of interest to researchers for a long time. Thus, controlling the polarization of the electrode contacting living cells, one can influence, for example, their proliferation or the synthesis of specific proteins. Moreover, the electrochemical approach formed the basis of the biocompatibility improvement of the materials contacting with body tissues that use in carbon hemosorbents and implants development. It became possible to reach a fundamentally new level in the study of cell activity with the introduction of optically transparent electrodes in this area. The use of such materials allowed approaching to the study of the influence of the electrode potential on adhesion activity and morphology of the different cell types (HeLa cells, endothelial cell, etc.) more detailed. There are a negligible number of publications in this area despite the obvious advantages of the usage of optically transparent electrodes to study living cells. This mini review is devoted to some aspects of the interaction of living cells with conductive materials and current advances in the use of optically transparent electrodes for the study of living cells, as well as the prospects for their use in cellular technologies.