Introduction
Spontaneous
abortion occurs in 15%~25% of clinical pregnancy,
among which about 5% women suffer from recurrent pregnancy
loss[1,2]. Patients who have previous pregnancy
loss experience tend to be more nervous and anxious, and are likely to
take examination more frequently. In early pregnancy inspection, doctors
hope to find cost-effective indicators to evaluate the pregnancy
conditions and predict pregnancy outcomes, so as to timely adjust the
treatment strategy and accurately make the decision to provide active
treatment or not. Serum β-human chorionic gonadotropin (β-HCG) and
progesterone (P) have been widely used in early pregnancy assessment,
but the clinical significance and value of progesterone test are still
controversial. Another reproductive hormone estradiol (E2) is also very
important in pregnancy maintenance, but has not been used as widely as
β-HCG and P. In this study, serum E2 and β-HCG levels were analyzed in
early pregnancy women, to explore the clinical significance of
dynamically monitoring E2 and β-HCG in assessing pregnancy conditions
and predicting pregnancy outcomes.