Impacts
- Study findings suggest that JEV might not be an immunising infection
in pigs. This has important implications where modelling studies
assuming long-term immunity are used to support public health
interventions. Longitudinal studies of pig immunity following natural
JEV infection are needed to test this hypothesis.
- JEV transmission in pigs occurs year-round in eastern Uttar Pradesh,
India, demonstrating potential for transmission to people if competent
mosquito vectors are present.
- Detailed, local environmental data are likely required to develop
models useful for public health surveillance in this endemic region,
where pig sero-surveillance is currently more likely to be useful to
confirm, rather than predict district-wise high risk periods and the
need to intensify public health resources to prevent JEV among people
in a district.