Author contributions
J.L., H.C. and H.S. conceived and designed the experiments; J.L., Q.H., J.S., T.L. and M.H. performed the experiments; J.L., T.L. and L.W. analysed the data and drafted relevant text; J.L., Q.H., H.C. and H.S. wrote the manuscript. H.S. sourced funding. All authors have read and approved the final version of this manuscript.