Correlation of strain parameters with myocardial function
We observed that LV-GS had a significant correlation with LVEF
(r=-0.726; 95% CI: -0.801 to -0.629) and LVMI (r=0.451; 95% CI:
0.296-0.582). Additionally, we found that LA-GS had its strongest
correlation with LA-Volume (r=-0.453, 95%CI: -0.584 to -0.298) and with
LVMI (r= -0.398, 95% CI: -0.538 to -0.236). In the prediction
of myocardial function, we found that LV-GS predicted 64.6% and LA-GS
14.1% of LVEF variability. Also, both LV-GS and LA-GS predicted LVMI
and RWT parameters (Figure 3 ). Exploring the subgroups of
subjects with previous myocardial infarction, we found that these
patients had lower LV-GS (p<0.001) and lower LA-GS
(p<0.032) compared to subjects without myocardial infarction.
As expected, these subjects also had decreased LVEF (p<0.001)
and eccentric hypertrophy with RWT (p<0.021) and LVMI
(p<0.113) (Supplementary Figure 2) .