Echocardiographic evaluation
All the echocardiographic data is shown in Table 2 . Briefly, median LVEF using 2D was 57% (IQR: 47-61) and by 3D 56% (IQR: 46.5-62), with median RWT of 0.38 (SD: 0.089), LVMI of 94 g/m2 (IQR: 77-109.5), LV-GS of -19.6% (IQR: -21.8 to -16.5) and LA-GS of 39.3% (IQR: 27.3-52.2) and LA-Reservoir Strain (LA-RS) of 39.1% (IQR:27.3-51.7). Among the different geometry groups, we found that the left ventricular parameters, LVEDd, LVESd, IVSd, PWd, S wave and E/e’ differed from group to group. As expected, we found that cardiac indexes showed differences in RWT, LV mass and LVMI. There were also differences among LA-volumes. In the evaluation of left ventricular and atrial strain, we found significant differences in LV-GS, LA-GS and LA-RS among our geometry groups. The eccentric hypertrophy group had the lowest LV-GS with a median of -17.68% (IQR: -19.82 to -13.6), and the concentric hypertrophy group had the lowest LA-GS and LA-RS with a median of 31.5% (IQR: 20.1-39.3) and 31.3 % (IQR: 19.9-39.3), respectively. Further evaluation of the left atrium showed that the eccentric hypertrophy group had the highest LA-volume and the lowest contraction phase (Table 3, supplementary Figure 1) . We found decreased LV-GS in 40 (33%) subjects, while decreased LA-GS or LA-RS was present in only 14 (11.5%) subjects, while the presence of both conditions was evident in 14 (11.5%) cases.