Figure 6. Glucocorticoids and pathway of oxidative stress. AKT (A) and p47phox (C) phosphorylation were analyzed in in human peripheral blood mononuclear cells (PBMCs) incubated with scalar concentrations (150–600 ng/ml) of betamethasone or methylprednisolone and stimulated with LPS (40pg/ml) (n = 3 experiments) (*p value < 0.05; **p value <0.001;***p value <0.0001; Kruskal–Wallis test). A representative western blot of AKT (B) and p47phox (D) phosphorylation in the presence or not of betamethasone or methylprednisolone (150–600 ng/ml).