Figure 5. Glucocorticoids and oxidative stress. Nox2 activation (A) and H2O2 production (B) were evaluated in human peripheral blood mononuclear cells (PBMCs) incubated with scalar concentrations (150–600 ng/ml) of betamethasone or methylprednisolone and stimulated with LPS (40pg/ml) (n = 5 experiments) (*p value < 0.05; **p value <0.001;***p value <0.0001; Kruskal–Wallis test).