Results
Survivors had decreased alpha diversity compared to controls (Shannon
index p=0.001, Simpson index p=0.032) and differently abundant bacterial
taxa. Further, among survivors, those who received radiation to the
central nervous system or abdomen/pelvis had decreased alpha diversity
compared to those that did not receive radiation (Shannon and Simpson
p<0.05 for both). Although, no specific component of metabolic
syndrome or cytokine was associated with measures of alpha diversity,
survivors with low adiponectin-lectin ratio, elevated body mass index,
and elevated C-Reactive protein had differently abundant taxa compared
to those with normal measures.