CrCl: Creatinine clearance; TIA: Transient ischemic attack; INR:
International normalized ratio
aCirrhosis or bilirubin >2× normal, or
aspartate aminotransferase/alanine aminotransferase/alkaline phosphatase
>3× normal
bINR > 1.1
Table 4. Multivariable analysis of subgroup analysis of factors
associated with bleeding events in patients on low-dose edoxaban