No events N = 314 Events N = 32
p-value
Age (years)
< 65 69 (22.0) 3 (9.4) 0.094
≥ 65 245 (78.0) 29 (90.6)
Sex
Male 165 (52.5) 13 (40.6) 0.199
Female 149 (47.5) 19 (59.4)
Weight (kg)
≤ 60 119 (37.9) 19 (59.4) 0.018
> 60 195 (62.1) 13 (40.6)
CrCl (mL/min)
15–50 91 (34.5) 8 (29.6) 0.613
> 50 173 (65.5) 19 (70.4)
Medical history
Congestive heart failure
Yes
49 (15.6)
2 (6.2)
0.196
No
265 (84.4)
30 (93.8)
Hypertension
Yes
204 (65.0)
16 (50.0)
0.094
No
110 (35.0)
16 (50.0)
Diabetes
Yes
101 (32.2)
9 (28.1)
0.640
No
213 (67.8)
23 (71.9)
Previous ischemic stroke or TIA
Yes
47 (15.0)
5 (15.6)
1.000
No
267 (85.0)
27 (84.4)
Vascular disease
Yes
4 (1.3)
1 (3.1)
0.386
No
310 (98.7)
31 (96.9)
Immobilization
Yes
7 (2.2)
1 (3.1)
0.544
No
307 (97.8)
31 (96.9)
Recent (≤1 month) trauma and/or surgery
Yes
4 (1.3)
0 (0.0)
1.000
No
310 (98.7)
32 (100.0)
Abnormal liver functiona
Yes
10 (3.2)
2 (6.2)
0.306
No
304 (96.8)
30 (93.8)
INR
Normal
168 (53.5)
18 (56.2)
0.767
Highb
146 (46.5)
14 (43.8)
Previous bleeding
Yes
43 (13.7)
8 (25.0)
0.112
No
271 (86.3)
24 (75.0)
Cancer
Yes
28 (8.9)
7 (21.9)
0.030
No
286 (91.1)
25 (78.1)
Medication
Antiplatelet agents
Yes 20 (6.4) 3 (9.4) 0.459
No 294 (93.6) 29 (90.6)
Steroids
Yes 7 (2.2) 1 (3.1) 0.544
No 307 (97.8) 31 (96.9)