No events N = 231 Events N = 27
p-value
Age (years)
< 65 43 (18.6) 3 (11.1) 0.433
≥ 65 188 (81.4) 24 (88.9)
Sex
Male 107 (46.3) 9 (33.3) 0.199
Female 124 (53.7) 18 (66.7)
Weight (kg)
≤ 60 125 (54.1) 20 (74.1) 0.048
> 60 106 (45.9) 7 (25.9)
CrCl (mL/min)
15–50 96 (50.8) 9 (40.9) 0.380
> 50 93 (49.2) 13 (59.1)
Medical history
Congestive heart failure
Yes
36 (15.9)
3 (11.1)
0.777
No
191 (84.1)
24 (88.9)
Hypertension
Yes
139 (61.2)
14 (51.9)
0.346
No
88 (38.8)
13 (48.1)
Diabetes
Yes
66 (29.1)
7 (25.9)
0.732
No
161 (70.9)
20 (74.1)
Previous ischemic stroke or TIA
Yes
44 (19.4)
6 (22.2)
0.726
No
183 (80.6)
21 (77.8)
Vascular disease
Yes
2 (0.9)
1 (3.7)
0.283
No
229 (99.1)
26 (96.3)
Immobilization
Yes
6 (2.6)
1 (3.7)
0.549
No
221 (97.4)
26 (96.3)
Recent (≤1 month) trauma and/or surgery
Yes
4 (1.8)
0 (0.0)
1.000
No
223 (98.2)
27 (100.0)
Abnormal liver functiona
Yes
4 (1.7)
1 (3.7)
0.427
No
227 (98.3)
26 (96.3)
INR
Normal
127 (55.0)
116 (59.3)
0.672
Highb
104 (45.0)
11 (40.7)
Previous bleeding
Yes
35 (15.4)
7 (25.9)
0.174
No
192 (84.6)
20 (74.1)
Cancer
Yes
20 (8.7)
5 (18.5)
0.157
No
211 (91.3)
22 (81.5)
Medication
Antiplatelet agents
Yes 19 (8.4) 3 (11.1) 0.714
No 208 (91.6) 24 (88.9)
Steroids
Yes 3 (1.3) 1 (3.7) 0.359
No 228 (98.7) 26 (96.3)