Materials and Methods
From June 2009 to June 2010, a total of 136 adult patients with IgAN were enrolled in the study. Glomerular deposition of the complement protein C3, immune complexes, and inflammatory cells were detected in renal biopsy tissue. The level of renal lesions, glomerular immune complexes, and the density of interstitial inflammatory cells were analyzed. Based on an average of 105 months of follow-up, the predictive value of glomerular C3 deposition for IgAN progression was investigated.