Name Type of oil Subject Intervention period Temperature Duration of heating Physiological changes
Adam et al. 2009a PO 30 female Sprague–Dawley rats 4 months 180 10mins, 1x Intima ⁄ media ratio; Atherosclerosis
Adam et al. 2009b (46) 10mins, 5x LDL-c; Atherosclerosis
Famurewa et al. 2017a 20 male Wistar strain rats 28 days 180 10mins, 5 days Weight gain; Obesity
Famurewa et al. 2017b (10) BP; Hypertension
Kamisah et al. 2015(12) 32 Sprague–Dawley rats 16 weeks 180 10mins, 5x BP; Hypertension
Kamisah et al. 2016 (11) 16 weeks 180 10mins, 5x
Nkanu et al. 2017a 30 male Wistar rats 16 weeks BP; Hypertension
TG levels; Atherosclerosis
Nkanu et al. 2017b (13)
Nurul Iman et al. 2013 (47) 32 male Sprague-Dawley rats 16 weeks 5x Weight gain; Obesity
Siti et al. 2017a (14) 56 male Sprague Dawley rats 16 weeks 180 15mins, 5x Intima ⁄ media ratio; Atherosclerosis
Siti et al. 2017b 15mins, 10x
Tan et al. 2012a 24 adult male Sprague-Dawley rats 6 months 180 10mins, 5x Intima ⁄ media ratio; Atherosclerosis
Tan et al. 2012b (48) 10mins, 10x
Bautista et al. 2014a CNO 48 male Wistar rats 10 weeks 190 10mins, 1x Visceral adipose tissue; Obesity
Bautista et al. 2014b (26) 10mins, 10x
Das et al. 2017a CO 30 male Sprague-Dawley rats 16 weeks 180 15mins, 1x Vasodilation; Hypertension
Das et al. 2017b 15mins, 5x
Das et al. 2017c (21) 15mins, 10x
Alonso and Martínez-González 2004 (49) EVOO 5573 humans included min 2 years of follow up 15mins Hypertension
Battino et al. 2002 (15) 16 male Wistar rats 8 weeks 180 TBARS; Oxidative stress
Farnetti 2011 (50) 12 obese, 5 lean women 2 weeks HOMA-IR; Diabetes
Rueda-Clausen et al. 2007a 10 healthy young men 9 weeks 200 8mins, 10x BP; Hypertension
Rueda-Clausen et al. 2007b (16) 8 mins, 20x
Salas-Salvado et al. 2011a 418 nondiabetic humans 4 years Waist circumference; Obesity
Salas-Salvado et al. 2011b (51) HOMA-IR; Diabetes
Salas-Salvado et al. 2014a 3541 patients 3 months of follow up Waist circumference; Obesity
Salas-Salvado et al. 2014b (52) Hypertension
Sayon-Orea et al. 2013 (17) 9850 men and women 4 weeks BMI; Obesity
Skowron et al. 2018 (53) 32 male rabbits 6 months 180 6 hours MDA; Oxidative stress
Sutherland et al. 2002 (54) 16 healthy men 1 week 210 8 hours LDL-c; Atherosclerosis
Aruna et al. 2005 (18) SFO Male Wistar rats 45 days 180 60 mins Weight gain; Obesity
Garrido-Polonio et al. 2004a 18 male Wistar rats 27 days 180 6hrs Weight gain; Obesity
Garrido-Polonio et al. 2004b (19) TBARS; Oxidative stress
Perez-Herrera et al. 2013(55) 20 obese people 8 weeks 180 5mins, 20x GSH/GSSG; Oxidative stress
Srivastava et al. 2010 (20) 50 male Wistar rats 1 week 280 30mins, 6x TBARS; Oxidative stress
Adam et al. 2008a SBO 24 healthy and mature female Sprague-Dawley rats 4 months 180 10mins, 1x TBARS; Oxidative stress
Adam et al. 2008b 10mins, 5x LDL-c; Atherosclerosis
Adam et al. 2008c
Adam et al. 2008d (56)
Adam et al. 2009a 30 female Sprague Dawley rats 4 months 180 10mins, 1x Weight gain; Obesity
Adam et al. 2009b (57) 10mins, 5x
Awney 2011 (58) 24 male Sprague-Dawley weanling rats 12 weeks 185 20mins, 5x Weight gain; Obesity
Chiang et al. 2011 (59) 24 male C57BL/6J mice 8 weeks 205 6 hrs, 4x TBARS; Oxidative stress
Chuang et al. 2013 (60) 40 female and male C57BL/6JNarl mice 12 weeks 205 6 hrs, 4x TBARS; Oxidative stress
Leong et al. 2010a 42 adult male Sprague-Dawley rats 24 weeks 180 10mins, 1x Weight gain; Obesity
Leong et al. 2010b 10mins, 2x
Leong et al. 2010c 10mins, 5x
Leong et al. 2010d (22) 10mins, 10x
Ng et al. 2012a 24 male Sprague-Dawley rats 6 months 180 10mins, 5x Aortic wall; Atherosclerosis
10mins, 10x
Ng et al. 2012b (61)
Rueda-Clausen et al. 2007a 10 healthy young men 9 weeks 200 8mins, 10x BP; Hypertension
Rueda-Clausen et al. 2007b (16) 8 mins, 20x
Yen et al. 2010 (23) 16 spontaneously hypertensive rats and 16 normotensive Wistar male rats 10 weeks 180 32hrs TBARS; Oxidative stress