Search strategy
The search was conducted through three different literature databases – PubMed, (http://www.ncbi.nlm.nih.gov/pubmed), CENTRAL (Central Register of Controlled Trials; http:// www.cochranelibrary.com/) and EMBASE (https://www.embase.com/). Published articles were searched from 2000 to 2020 for randomized controlled feeding trials, cohort, and case-control studies. Several different combinations of keywords were used: frying oil, heated vegetable/plant oils, heated PO/CNO/CO/EVOO/SFO/SBO, thermally oxidized, repeatedly heated vegetable oil, obesity, weight gain, atherosclerosis, high blood pressure, hypertension, Type 2 diabetes, and oxidative stress in all animals and human studies. Besides that, reference lists of relevant articles were scanned to identify potential articles not included in the databases.