Title:
CAR-T cell therapy in less than 2 year old children with infant acute
lymphoblastic leukemia : case reports and review of the literature
Authors:
L. Cimasoni1, J. Sartoretti1, F.
Ceppi2, SL. Maude3, N.
Bodmer4, M. Hauri-Hohl4, P.
Bader5, F. Baleydier1, F.
Bernard1, M. Ansari1
1 Pediatric Oncology and Hematology Unit, Department
of Pediatrics, Geneva Children’s Hospital, University Hospital of
Geneva, Geneva, Switzerland; and Cansearch Research Laboratory,
University of Geneva.
2 Pediatric Hematology-Oncology Unit, Division of
Pediatrics, Department Woman-Mother-Child, Lausanne University Hospital,
Lausanne, Switzerland.
3 Division of Oncology, The Children’s Hospital of
Philadelphia, Philadelphia, PA.
4 Pediatric Stem Cell Transplantation Unit, Department
of Pediatrics, Zurich Children’s Hospital, Zurich, Switzerland
5 Division for Stem Cell Transplantation and
Immunology, Department for Children and Adolescents, University
Hospital, Goethe University, Frankfurt/Main, Germany
Acknowledgements: R. Renella2, M.
Beck-Popovic2, S. Kroiss4, JP
Bourquin4
Corresponding author :
Dr Laurent Cimasoni
Hôpitaux universitaires de Genève (HUG)
Département d’onco-hématologie pédiatrique
Rue Willy-Donzé 6
1205 Genève / CH
laurent.cimasoni@hcuge.ch/ +4179.885.90.85
Word Count : Abstract 80 words, Main text 1494 words
Table and Figure : Table 1, Figure 1 (1A and 1B)
Key words : Infant ALL, CAR-T cell therapy, Tisagenlecleucel, case study
Abbreviations :