Commitment to confidentiality and ethical consideracions
The EAHFE registry was approved by the regional Ethics Committee of Clinical Investigation of the Principality of Asturias. All the patients provided signed informed consent for participation in the study and posterior follow-up. The data were encoded and managed with complete confidentiality and were only accessible to the investigators of each of the participating centers. The ANEM-AHF study was performed according to the principles of the Declaration of Helsinki for biomedical investigation.