Study Population
Our target population consisted of HIV-related hospitalizations from
January 1, 2005 to December 21, 2014. We included hospital admissions
with a diagnosis of HIV infection (International Classification of
Diseases, Ninth Revision, Clinical Modification [ICD-9-CM] code 042
and V08) in primary and secondary diagnostic field during our study
period. We excluded patients with missing information about sex,
mortality, age and age less than 18 years Since NIS represents a 20%
stratified random sample of US hospitals, analyses were performed using
hospital-level discharge weights provided by the NIS to obtain national
estimates gave our final population of HIV patients. We subclassified
this group into hospitalizations with associated cardiac arrhythmia and
those without arrhythmia for trend analysis using ICD codes for cardiac
arrhythmias such as ventricular tachycardia (VT), ventricular
fibrillation (VF)/flutter, supraventricular tachycardia (SVT), AF and,
atrial flutter(AFL) listed in Supplementary table 1. Interventions such
as ICD implantation, use of vasopressors, cardiac catheterization,
endotracheal intubation and CPR were identified by ICD codes in both
primary and secondary procedural field (Supplementary Table 1).