Th1 |
No significant change during reproductive cycle |
[33] |
Th2 |
Diminished during mid-luteal phase as compared to early follicular
phase |
[33] |
Th1/Th2 ratio |
No significant change during reproductive cycle |
[33] |
Th17 |
Lower number in pregnancy state compared to non-pregnancy state |
[123] |
|
No difference in circulating Th17 cells between all trimesters and
non-pregnancy state |
[124] |
|
No difference in circulating Th17 cells between certain pregnancy
period and non-pregnancy period |
[105, 125] |
|
Higher in decidua as compared to blood during first trimester |
[124] |
Tregs |
Density gradually increases during proliferative phase in
peripheral blood and endometrium |
[126] |
|
Increase progressively in peripheral blood during first and second
trimester while as decrease during third trimester as well as
post-partum |
[5,127] |
|
Suppressive action increased during first and second trimester while
as weakened during third trimester compared to non-pregnant women |
[128] |
|
Elevated in peripheral blood during late follicular phase compared to
luteal phase |
[52] |
Th17/Treg
Ratio
|
Lower in pregnancy as compared to non-pregnancy state
|
[123]
|
|
Reduced during second and third trimester of pregnancy compared to
non-pregnancy women |
[129] |