Results
In the current study, 39 cirrhotic patients and 41 age‐ and sex‐matched
healthy participants were studied. Table 2 is a presentation of
the demographic features and laboratory findings for the patients with
cirrhosis and healthy subjects. Both groups were not dissimilar
regarding the clinical properties. In terms of laboratory findings,
white blood cell count, haemoglobin, platelet count, creatinine, sodium,
and albumin were significantly decreased in the cirrhotic cases, while
their alanine transaminase, aspartate transaminase, total bilirubin,
indirect bilirubin, and prothrombin time were significantly elevated
(p < 0.05, for each parameter). The other laboratory
results were fairly similar for each group. We noted that no significant
differences were present between each group in the many standard
echocardiographic parameters in which the diameter and functions of the
right and left spaces were evaluated (Table 3 ). However, PAS
was measured as 23.62 ± 5.87 (Hz/msn) in the cirrhotic cases and 19.09 ±
4.16 (Hz/msn) in the healthy subjects (p < 0.001).
Fifteen cirrhotic patients (%38.4) were clinically decompensated in the
study, but there was no statistically significant dissimilarities in
terms of echocardiographic parameters for compensated or decompensated
cirrhotic patients (Table 4 ).
A positive statistical relevance was found between PAS and sPAP
(r = 0.378; p = 0.001), and a negative statistical
relevance was found with PfAT and sPAP (r = −0.314; p =
0.005). An elevated PAS values was positively associated with sPAP
(p < 0.05) (Fig. 2 ). The interactions of the
echocardiographic parameters with age, BMI, disease period, and PAS in
cirrhotic patients are shown in Table 5 .
The independent effects of probable demographic and echocardiographic
parameters associated with cirrhosis disease were evaluated by
univariate and multivariate LR analysis. Following applying of the
univariate analysis, five parameters were statistically significance
with cirrhosis disease (sPAP, PAS, LA diameter, RV annular diameter, and
E/e’); the variables, which were applied into the multivariate analysis,
are shown in Table 6 . The multivariate analysis found that PAS
(OR: 1.209; 95% CI: 1.059–1.381; p = 0.005), sPAP (OR: 1.201;
95% CI: 1.057–1.365; p = 0.005), and LA diameter (OR: 1.396;
95% CI: 1.079–1.805; p = 0.011) were independently linked with
cirrhosis disease.