STUDY LIMITATIONS
1) Whilst LSPSAF is considered more like a LA disease, to what extent
the RA contributes to the role in the development and maintenance of AF
remains unclear. Whether RA voltage-defined fibrosis, not assessed in
our study, could improve risk stratification in LSPSAF patients should
be analysed in future research investigations 2) The accuracy of LA
voltage mapping might have been influenced by several factors, such as
mapping following PVI or using voltage cut-off values <0.5mV.
We cannot further exclude the fact that the overall LVA burden might
have been altered due to the exclusion of patients not able to maintain
sinus rhythm, presenting LAA thrombus or if another method of LVA
detection had been applied 3) Women were underrepresented in the study