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The Contribution of Neurocognitive Situation, Physical Capacity and Daily Life Activities to Quality of Life after Childhood Acute Lymphoblastic Leukemia
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  • Elif KELESOrcid,
  • Yagmur Çam,
  • Bülent Elbasan,
  • Azime Şebnem Soysal Acar,
  • Zühre Kaya,
  • İdil Yenicesu,
  • Ulker Kocak
Elif KELES
Orcid
Gazi University Faculty of Medicine
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Yagmur Çam
Gazi University
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Bülent Elbasan
Gazi University
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Azime Şebnem Soysal Acar
Gazi University Faculty of Medicine
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Zühre Kaya
Gazi University Faculty of Medicine
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İdil Yenicesu
Gazi University Medical Faculty
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Ulker Kocak
Gazi University, Faculty of Medicine
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Abstract

Background There are no extensive studies on the quality of life of (QL) in children who completed ALL treatment and currently living without any disease in Turkey. Our study aimed to analyze both the QL and the effects of physical, neurocognitive capacities on QL of children aged between 7-12 years who received treatment for ALL. Methods Pediatric Quality of Life Scale (PedsQL) cancer module 3.0 child and proxy report, for ages 5-7 and 8-12 years, WeeFIM scale, Bruininks-Oseretsky motor competency test short form (BOT-2), Raven progressive test matrices(RPM), reading, writing and mathematics assessment tools and sociodemographic information form were carried out to obtain information from the children and their family. Results There was no effect of the months since the remission on pain, anxiety, cognitive problems, perceived physical appearance, and the total QL scores of children and proxy reports (p > 0.05). The physical capacities of children were significantly worse than healthy controls and have not reached the level of healthy children even after a long time since remission. There was a significant association between physical capacity and daily independent living status(p<0.001). Reading, writing and mathematical skills were significantly associated with the duration of remission (p<0.001) and the total score of Raven and PedsQL of those with mathematical difficulties were significantly lower than those without any difficulty(p<0.05).