Meta-analysis of the Efficacy of Magnetic Stimulation for Female Stress
ABSTRACT Objective: Female stress urinary incontinence is one of the
common diseases in menopausal women, which brings great inconvenience to
life. We conducted a meta-analysis to evaluate the efficacy of magnetic
stimulation (MS) in treating female stress urinary incontinence (SUI).
Methods: The electronic databases (E-DB) MEDLINE, EMBASE and Cochrane
Controlled Trial Registry system was used to retrieve the randomized
controlled trials (RCTs) which recorded MS as a remedy to female SUI.
Reference lists of related papers were carefully studied. Results: Six
RCTs exploring the effect of MS in the treatment of female SUI were
studied. We found that the MS group enjoyed a higher quality of life
(QoL) (MD of 0.59, 95% CI of 0.23 to 0.95, P=0.001) and lower
International Consultation on Incontinence Questionnaire (ICIQ) scores
(MD of -3.93, 95% CI of -5.86 to -2.01, P<0.0001) and
provided a higher objective cure rate (odds ratio [OR] of 8.49, 95%
CI of 3.08 to 23.37) compared with the placebo group. Apart from this,
MS treatment reduced the number of episodes of urinary incontinence (MD
of -1.42, 95% CI of −2.24 to −0.59, P=0.0007) and urine loss on pad
test (MD of −4.67 and 95% CI of −8.05 to −1.28, P=0.007). No
significant treatment-related adverse reactions were reported.
Conclusion: MS treatment showed a positive effect in the treatment of
SUI and further trials are required to specify the best protocol to
optimize the effect.