CONCLUSION
These were the first descriptions of AIH cases in Madagascar. AIH is a diagnostic challenge in low-income countries, requiring the use of diagnostic score and initial trial corticosteroid therapy. In two observations, the diagnostic of AIH was retained on clinical, biological, radiological and immunological arguments. Autoimmune liver disease is a real problem in low-resource countries. Therefore, a large-scale study on a Malagasy population seems necessary taking the epidemiological, therapeutic, prognostic aspects.