Discussion
We report a novel finding in marijuana induced bradyarrythmia.
Reversible high grade atrioventricular (AV) block with
electrophysiologic determination of site of conduction blockade is not
reported previously. The mechanism of bradyarrythmia is thought to be
mediated by increased vagal tone. However direct toxic effects of
Δ9-tetrahydrocannabinol (THC), through cannabinoid receptors 1(CB1R ) on
the cardiac conduction system cannot be ruled out.