aMedian (min, max) is reported for Tmax.
n=number of patients with corresponding evaluable pharmacokinetic parameters.
Abbreviations: AUCinf, area under the concentration-time curve from time zero to infinity; AUClast, area under the concentration-time curve from time zero to the last quantifiable concentration; CL/F, apparent total body clearance from plasma; Cmax, maximum concentration; Geo-CV, geometric coefficient of variation; Geo-mean, geometric mean; T1/2, elimination half-life determined as 0.693/λz; Tmax, time to reach maximum plasma concentration; λz, terminal elimination rate constant; Vz/F, apparent volume of distribution during the terminal elimination phase.