What is known?
Over the last decade non-alcoholic fatty liver disease (NAFLD) has
become the most common chronic liver disease in Western world. There are
still no approved therapy for NAFLD treatment. Some authors have
published data about beneficial effects of coffee consumption in
diabetes mellitus, while some other reported its usefulness in the
context of fibrosis, cirrhosis, and hepatocellular carcinoma in chronic
hepatitis C infected patients. Some reports had shown that short sleep
duration was associated with NAFLD prevalence, while some other studies
reported that that long sleep duration related to incident NAFLD.
Finally, smoking is an acknowledged risk factor for developing metabolic
syndrome, which is risk factor for NAFLD development.