3.1 Clinical and laboratory characteristics in HT patients.
This cross-sectional study included 120 women with HT among the studied
cases, 75 women were fertile, and 45 women had UEI, there were
statistically significant increases of the age of menarche, TSH,
anti-TPO, anti-TG, serum IFN- γ, IFN- γ mRNA, in UEI group as compared
to fertile group (P< 0.05). On the other hand, there were
significantly lower values of AMH as AFC compared to the fertile group
(P< 0.05). (Table 1).
3.6. The Accuracy ofcirculatingserum
IFN- γ (pg/mL), for the diagnosis ofUEI in patients of HT by
ROC analysis
Regarding its power in differentiating fertile women from women with
UEI, the AUC was 0.984 (95% CI = 0.957–1.000) with sensitivity =
99.6%, specificity = 96%, and the cutoff values (16.7 pg/mL), (Figure
1).
3.7. The Accuracy ofcirculating
IFN- γ gene expression for diagnosis of UEI in patients of HT by ROC
analysis
Regarding the power in differentiating fertile women from women with
UEF. The AUC was 0.912 (95% CI = 0.860–0.965) with sensitivity =
90.4%, specificity = 94.2%, and the cutoff values (2.65), (Figure 2).
3.8. The Accuracy of thecombination of circulating
serum IFN- γ and IFN- γ gene expression for diagnosis of UEI in patients
of HT by ROC analysis
Regarding the power in differentiating fertile women from women with
UEF. The AUC was 0.953 (95% CI = 0.889–1.000) with sensitivity =
90.4%, specificity = 94.2%, (Figure 3).