3.1 Clinical and laboratory characteristics in HT patients.
This cross-sectional study included 120 women with HT among the studied cases, 75 women were fertile, and 45 women had UEI, there were statistically significant increases of the age of menarche, TSH, anti-TPO, anti-TG, serum IFN- γ, IFN- γ mRNA, in UEI group as compared to fertile group (P< 0.05). On the other hand, there were significantly lower values of AMH as AFC compared to the fertile group (P< 0.05). (Table 1).
3.6. The Accuracy ofcirculatingserum IFN- γ (pg/mL), for the diagnosis ofUEI in patients of HT by ROC analysis
Regarding its power in differentiating fertile women from women with UEI, the AUC was 0.984 (95% CI = 0.957–1.000) with sensitivity = 99.6%, specificity = 96%, and the cutoff values (16.7 pg/mL), (Figure 1).
3.7. The Accuracy ofcirculating IFN- γ gene expression for diagnosis of UEI in patients of HT by ROC analysis
Regarding the power in differentiating fertile women from women with UEF. The AUC was 0.912 (95% CI = 0.860–0.965) with sensitivity = 90.4%, specificity = 94.2%, and the cutoff values (2.65), (Figure 2).
3.8. The Accuracy of thecombination of circulating serum IFN- γ and IFN- γ gene expression for diagnosis of UEI in patients of HT by ROC analysis
Regarding the power in differentiating fertile women from women with UEF. The AUC was 0.953 (95% CI = 0.889–1.000) with sensitivity = 90.4%, specificity = 94.2%, (Figure 3).