Measures of treatment outcomes
The targeted lipid control rates were considered as LDL-C levels goals under 1.0mmol/L or 1.4mmol/L. Cardiovascular events were defined as a total of death, MI, TVR, re-angina and re-hospitalization for cardiac events. Death was considered to be of cardiac origin unless an alternate cause was unequivocally established, even in participants with serious non-cardiac comorbidities. Spontaneous MI was defined as the presence of clinical or electrocardiographic changes consistent with myocardial ischemia and circulating cardiac biomarker concentrations above the upper limit of normal, in accordance with the universal definition [12]. TVR was defined as the requirement for a repeated percutaneous intervention or surgical bypass of any segment of a target vessel. A target vessel was defined as the entire major coronary vessel proximal and distal to the target lesion, which included the upstream and downstream branches and the target lesion itself.