Insert Figure 1
There were two main results distribution, i.e., lower and higher than
60mmol/L and 80mmol/L, respectively, with no intermediate values. A
strong, statistically significant correlation
(rs = 0.83; P < .05) between the two
concomitant assays was found; moreover, the difference between the 95%
CI lower and upper limits (0.08), denotes high accuracy of our results.
Although SC is used worldwide, to the best of our knowledge there is no
previous work that had been attempted to assess its repeatability,
regardless the age group. Therefore, the unavailability of previous
studies hinders comparisons with our results.
In conclusion, the strong, statistically significant repeatability found
in the present study, testify to the clinical usefulness of SC, adds
original evidence, and reinforces its role as a reliable screening test
for CF.
ACKNOWLEDGMENT
We would like to acknowledge Roberto Vagner Puglia Ladeira, the
Laboratory Coordinator, for supporting the study.
CONFLICT OF INTERESTS
The funding organization(s) played no role in the study design; in the
collection, analysis, and interpretation of data; in the writing of the
report; or in the decision to submit the report for publication.
AUTHOR CONTRIBUTIONS
RMB contributed to manuscript conception, writing, revision and editing.
CGA contributed to manuscript conception, writing, editing and to
critical revision of the manuscript. OGS contributed to data collection,
interpretation and analysis. DN supervised and/or performed SC assays.
JVAJ and FHP contributed to data collection, analysis, validation, and
interpretation, and writing of the manuscript. PC conceived the study,
and the study design; investigation, methodology, funding acquisition,
project administration, resources, validation; manuscript conception,
writing, editing and to critical revision of the manuscript.
ORCID
Paulo Camargos http://orcid.org/0000-0003-4731-291X
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