Figure Legends
Figure 1. Experimental Setup and Weight Loss Graph. A)Experimental groups and the daily treatment were shown in the table.B) Weight loss is shown as % loss compared to initial weight.
(n=5-8 mice per group).
Figure 2. Vit D improves mucositis pathology. A)Representative histology pictures from small intestine of each
experimental group. B) Histological scores were charted. *
indicates p<0.05. (n=5-8 mice per group).
Figure 3. Vit D augments intestinal IL-22. ELISA results forex-vivo ileal tissue culture supernatants (24 h culture). *
indicates p<0.05; ** indicates p<0.01, (n=5-8 mice
per group).
Figure 4. Expression of proinflammatory genes during mucositis
in the intestinal tissue upon Vit D treatment and IL-22 overexpression.Relative gene expression of il23p19, Ifng, Tnfa and Il10 .