Introduction
Thrombotic microangiopathies (TMAs) are a group of rare disorders that are characterized by microangiopathic hemolytic anemia and thrombocytopenia with thrombosis of the microvasculature. This is often associated with organ dysfunction and encompass congenital and acquired etiologies[1]. Distinguishing between these disorders is important, as many TMAs are life-threatening.
Acquired B12 deficiency is overlooked because of its rarity in developed countries[2]. Hematologic manifestations of B12 deficiency can include pancytopenia because of ineffective hematopoiesis. Defective red blood cells (RBCs) undergo phagocytosis in the marrow and as a result mimic an intravascular hemolytic process.
We describe the case of a 17- year-old male who had a history of intestinal resection and celiac disease which lead to a pseudo – TMA through malabsorption of vitamin B12.