Introduction
Thrombotic microangiopathies (TMAs) are a group of rare disorders that
are characterized by microangiopathic hemolytic anemia and
thrombocytopenia with thrombosis of the microvasculature. This is often
associated with organ dysfunction and encompass congenital and acquired
etiologies[1]. Distinguishing between these disorders is important,
as many TMAs are life-threatening.
Acquired B12 deficiency is overlooked because of its rarity in developed
countries[2]. Hematologic manifestations of B12 deficiency can
include pancytopenia because of ineffective hematopoiesis. Defective red
blood cells (RBCs) undergo phagocytosis in the marrow and as a result
mimic an intravascular hemolytic process.
We describe the case of a 17- year-old male who had a history of
intestinal resection and celiac disease which lead to a pseudo – TMA
through malabsorption of vitamin B12.