PrediXcan analysis of Asthma on chromosome 6
We identified the differentially expressed genes on chromosome 6 with the imputed mRNA expression levels for lung tissue and whole blood. At the false-discovery rate-adjusted 0.05 significance level, all significant genes are shown in Table 3. Significant results were observed for various HLA genes. The most significant result was found from HLA-DQA1 in lung tissue (8×10-8). In addition, HLA-DQB1 was significant expressed gene in lung tissue (6×10-4) and whole blood (3×10-4).