a, unpaired t-test; b, Mann-Whitney U test; c, chi-square test; d, Standard Deviation ;e, Ideal Body Weight(Kg); f, ICD 10 code definition: ”B: Certain infections,G: Diseases of nervous system, I: Disease of circulatory system, K: Disease of digestive system, T: Injury to different part of body region.”; g, Sequential Organ Failure Assessment (SOFA);h, Augmented Renal Clearance (ARC); i, Augmented Renal Clearance in Trauma Intensive Care (ARCTIC); j, creatinine clearance of 12-hour urine collection(ml/min)
Table3. Pharmacokinetic data