Summary:
Total 82 studies were included in which 12 studies represented vitamin D
levels in healthy individuals (Table 1) and 70 studies (Table 2) in
different conditions. It found that vitamin D deficiency is prevalent in
all parts of the country and about 64.6% healthy subjects had vitamin D
levels less than 30 ng/mL. Moreover, 70 studies showed its deficiency in
some diseases such as musculoskeletal, bone and periodontal problems,
nursing mothers and children, tuberculosis, diabetes, cardiovascular
problems and some type of cancers.
Women were found more deficient than men due to the cultural norms and
clothing style in this population. Some previous studies in different
parts of the world also showed that cultural norms and dress style were
associated with vitamin D deficiency in women (134-136).
Limited studies have been conducted to see the association of genetic
variations with some diseases. The results of such studies could not
establish any significant association with different diseases. This
could be due to the small sample size with limited scope of the study.