All patients (n=100) 1. PAF group (n=51) 2. Non-PAF group (n=49) P value (1 vs 2) 3. Normal/Mildly enlarged LA group (n=68) 4. Moderately enlarged LA group (n=21) 5. Severely enlarged LA group (n=11) P value (ANOVA)
Total surface area of LA (cm2) 78.8±19.7 69.2±13.6 88.8±20.2 <0.0001 76.3±18.0 82.6±23.3 87.3±20.9 0.1366
Number of mapping point 4580±1035 4331±939 4840±1076 0.0132 4504±1056 4593±932 5029±1068 0.298
Global LA activation time (ms) 112±21 101±15 124±21 <0.0001 110±20 120±24 115±20 0.1151
Global LA voltage (mV) 5.3±2.2 6.2±2.0 4.4±2.0 <0.0001 5.8±2.2 5.0±2.1 3.2±1.5 0.0011
Incidence of ACZ, n (%) 95 (95%) 46 (90%) 49 (100%) 0.0245 63 (93%) 21 (100%) 11 (100%) 0.2899
Length of ACZ (cm) 5.48±4.00 3.81±2.95 7.22±4.23 <0.0001 4.94±4.02 6.27±4.56 7.78±3.83 0.0469
Number of ACZ 2.2±1.4 1.6±1.0 2.6±1.1 <0.0001 1.9±1.1 2.1±1.1 2.9±1.1 0.1977
CoA (cm2) 6.0±4.1 5.5±4.2 6.5±3.9 0.2196 5.5±4.2 7.1±3.8 7.0±3.3 0.2139
Number of CoA 1.9±0.6 1.8±0.5 1.9±0.7 0.2601 1.7±0.6 2.1±0.5 2.2±0.6 0.0049
Overlapping rate of CoAs and ACZ (%) 25.6±28.0 26.5±33.1 24.6±21.6 0.7314 23.9±28.5 28.0±29.2 31.4±23.0 0.6476
Incidence of mild LVA (<1.3 mV), n (%) 78 (78%) 36 (71%) 42 (86%) 0.0679 50 (74%) 17 (81%) 11 (100%) 0.1353
Burden of mild LVA (cm2) 19.1±16.5 13.5±13.3 24.9±17.7 0.0004 15.1±14.4 23.7±18.4 34.8±14.7 0.0003
Overlapping rate of mild LVA and ACZ (%) 51.2±36.2 42.1±36.2 60.6±34.0 0.0099 42.3±33.3 66.4±36.3 83.0±24.9 <0.0001
Incidence of moderate LVA (<1.0 mV), n (%) 56 (56%) 23 (45%) 33 (67%) 0.025 32 (47%) 13 (62%) 11 (100%) 0.0038
Burden of moderate LVA (cm2) 10.0±10.7 6.4±7.8 13.8±12.1 0.0004 7.3±8.6 12.1±11.5 22.9±11.9 <0.0001
Overlapping rate of moderate LVA and ACZ (%) 32.9±32.8 24.8±30.4 41.4±33.3 0.0109 24.3±27.5 43.7±38.2 65.7±26.6 <0.0001
Incidence of severe LVA (<0.5 mV), n (%) 20 (20%) 3 (6%) 17 (35%) 0.0003 6 (9%) 8 (38%) 6 (55%) 0.0001
Burden of severe LVA (cm2) 2.9±5.3 1.0±1.9 5.0±6.8 <0.0001 1.5±2.9 3.6±4.7 10.9±9.7 <0.0001
Overlapping rate of severe LVA and ACZ (%) 14.6±22.0 10.3±19.9 18.9±23.5 0.0502 9.4±17.6 19.9±24.4 36.4±27.9 0.0002