White blood cell count, × 10⁹/L |
4.00-10.00 |
6.66 (4.54-9.61) |
5.98
(3.71-7.43) |
9.27 (5.86-12.83) |
0.002 |
<4 |
|
13 (22%) |
9 (27%) |
4 (15%) |
0.004 |
4–10 |
|
33 (56%) |
22 (67%) |
11 (42%) |
|
>10 |
|
13 (22%) |
2 (6%) |
11 (43%) |
|
Neutrophil count, × 10⁹/L |
1.80-6.30 |
4.50 (2.73-7.99) |
4.12
(2.36-5.42) |
8.16 (3.90-12.00) |
0.001 |
Lymphocyte count, × 10⁹/L |
1.10-3.20 |
0.84 (0.53-1.44) |
1.14
(0.80-1.73) |
0.56 (0.28-0.76) |
0.000 |
<1·1 |
|
38 (64%) |
16 (48%) |
22 (85%) |
0.004 |
≥1·1 |
|
21 (36%) |
17 (52%) |
4 (15%) |
|
Macrophages, × 10⁹/L |
0.10-0.60 |
0.51 (0.35-0.63) |
0.51 (0.36-0.66) |
0.52 (0.33-0.63) |
0.891 |
Eosinophil count, × 10⁹/L |
0.02-0.52 |
0.02 (0.00-0.08) |
0.04 (0.02-0.11) |
0.00 (0.00-0.02) |
0.000 |
<0.02 |
|
27 (46%) |
8 (24%) |
19 (73%) |
0.000 |
≥0.02 |
|
32 (54%) |
25 (76%) |
7 (27%) |
|
Basophils, × 10⁹/L |
0.00-0.10 |
0.01 (0.01-0.03) |
0.01 (0.01-0.03) |
0.01 (0.01-0.03) |
0.657 |
Haemoglobin, g/L |
130.0-175.0 |
129.0 (112.0-139.0) |
134.0
(116.5-141.0) |
125.5 (109.0-134.8) |
0.184 |
Platelet count, × 10⁹/L |
125.0-350.0 |
213.0 (143.0-272.0) |
216.0
(166.0-279.5) |
176.0 (85.5-244.5) |
0.145 |
<125 |
|
10 (17%) |
2 (6%) |
8 (31%) |
0.012 |
≥125 |
|
49 (83%) |
31 (94%) |
18 (69%) |
|
Ferritin, µg/L |
30-400 |
534.60 (219.80-1355.63) |
293.55
(201.90-581.00) |
1264.20 (577.45-1889.55) |
0.004 |
Erythrocyte sedimentation rate, mm/H |
0-15 |
31.50 (15.00-59.75) |
40.00 (16.50-59.50) |
26.00 (15.00-74.00) |
0.872 |
D-dimer, µg/mL |
≤0·5 |
1.73 (0.49-2.74) |
0.65 (0.40-2.17) |
2.69
(1.44-8.99) |
0.001 |
≤0·5 |
|
14/57 (25%) |
12/31 (39%) |
2 (8%) |
0.001 |
>0·5 to ≤1 |
|
7/57 (12%) |
6/31 (19%) |
1 (4%) |
|
>1 |
|
36/57 (63%) |
13/31 (42%) |
23 (88%) |
|
Creatine kinase, U/L |
≤190 |
85.50 (47.50-196.00) |
65.00
(38.00-162.25) |
127.00 (60.50-446.50) |
0.065 |
Lactate dehydrogenase, U/L |
135-225 |
260.00 (223.00-471.00) |
230.00
(200.00-280.00) |
471.00 (291.00-628.00) |
0.000 |
≤225 |
|
15 (25%) |
14 (42%) |
1 (4%) |
0.001 |
>225 |
|
44 (75%) |
19 (58%) |
25 (96%) |
|
Hypersensitive troponin I, pg/mL |
≤34.2 |
7.60 (3.03-44.70) |
4.10
(1.95-14.15) |
33.40 (4.55-281.85) |
0.001 |
≤34.2 |
|
40/54 (74%) |
27/29 (93%) |
13/25 (52%) |
0.001 |
>34.2 |
|
14/54 (26%) |
2/29 (7%) |
12/25 (48%) |
|
Alanine aminotransferase, U/L |
≤41 |
24.00 (15.00-40.00) |
22.00
(14.00-39.50) |
24.50 (17.50-69.00) |
0.205 |
≤41 |
|
45 (76%) |
27 (82%) |
18 (69%) |
0.259 |
>41 |
|
14 (24%) |
6 (18%) |
8 (31%) |
|
Aspartate aminotransferase, U/L |
≤40 |
32.00 (19.00-50.00) |
23.00
(18.50-39.50) |
45.50 (21.50-89.25) |
0.003 |
≤40 |
|
37 (63%) |
26 (79%) |
11 (42%) |
0.004 |
>40 |
|
22 (37%) |
7 (21%) |
15 (58%) |
|
Blood urea nitrogen, mmol/L |
3.6-9.5 |
5.10 (3.80-8.30) |
4.70
(3.75-5.60) |
7.90 (4.50-15.15) |
0.004 |
≤9.5 |
|
47 (80%) |
32 (97%) |
15 (58%) |
0.000 |
>9.5 |
|
12 (20%) |
1 (3%) |
11 (42%) |
|
Creatinine, μmol/L |
59-104 |
74.00 (61.00-94.00) |
72.00 (61.00-86.50) |
80.50 (60.00-123.25) |
0.136 |
≤104 |
|
49 (83%) |
32 (97%) |
17 (65%) |
0.001 |
>104 |
|
10 (17%) |
1 (3%) |
9 (35%) |
|
Procalcitonin, ng/mL |
<0.05 |
0.08 (0.04-0.31) |
0.04
(0.03-0.07) |
0.18 (0.08-1.37) |
0.000 |
<0·05 |
|
18/55 (33%) |
17/30 (57%) |
1/25 (4%) |
0.000 |
≥0·05 |
|
37/55 (67%) |
13/30 (43%) |
24/25 (96%) |
|
High-sensitivity C-reactive Protein (hs-CRP), mg/L |
<1 |
30.55 (4.33-124.28) |
19.85 (1.93-34.05) |
126.15 (27.68-188.43) |
0.000 |
<3 |
|
14/58 (24%) |
11/32 (34%) |
3 (12%) |
0.043 |
≥3 |
|
44/58 (76%) |
21/32 (66%) |
23 (88%) |
|
IL-1β, pg/mL |
<5 |
5.00 (5.00-5.00) |
5.00 (5.00-5.00) |
5.00
(5.00-5.00) |
0.245 |
IL-2R, U/L |
223-710 |
645.00 (406.50-1068.00) |
499.50 (337.25-734.25) |
973.00 (602.00-1919.00) |
0.000 |
IL-6, pg/mL |
<7 |
11.59 (2.34-57.00) |
5.68 (1.83-29.56) |
47.42 (8.64-167.20) |
0.002 |
IL-8, pg/mL |
<62 |
14.40 (7.90-47.10) |
11.20 (5.40-21.05) |
34.10 (12.95-81.00) |
0.001 |
IL-10, pg/mL |
<9.1 |
5.00 (5.00-7.20) |
5.00 (5.00-5.00) |
6.30 (5.00-19.45) |
0.001 |
TNFα, pg/mL |
<8.1 |
9.20 (5.75-12.90) |
7.65 (4.60-10.83) |
11.80 (7.50-17.30) |
0.021 |