INTRODUCTION
The pandemic caused by SARS-CoV-2, most commonly known as Coronavirus
disease 2019 (COVID-19), is one of the most important challenges
humanity is facing nowadays, pushing health systems around the world to
maximum capacity, leading to the collapse in intensive care units
[1].
Its clinical forms vary from asymptomatic to mild, moderate, and severe
symptoms, leading to fatal events in many cases. One of the most common
symptoms is the development of an acute respiratory disease, which can
lead to respiratory or multi-organ failure [2].
Current research has identified, several risk factors for severe
outcomes. The most important factors include old age, hypertension,
diabetes, cardiovascular disease, tobacco exposure, malignancies, and
immunosuppression [3]. Initially, asthma was thought to be a risk
factor for SARS-CoV-2 infection, as COVID -19 primarily affects the
respiratory system; surprisingly, many are the reports, and large case
series published that remark the low prevalence of asthma among COVID
-19 patients [4-8], including those admitted in the intensive care
unit, who required mechanical ventilation (1.8%) [9].
The main purpose of this study is to analyze the personal
characteristics in severe asthma patients in treatment with monoclonal
antibody (MAB), belonging to the Health Department of Castellon’s
University General Hospital, (Castellon, Spain), in order to see which
behavioral and social circumstances obey patients, and if these
variables affect in any way the probability of being infected by
COVID-19 or not. Secondly, we wanted to investigate the prevalence of
COVID-19 in these patients.