Methods
We compiled English language articles that reported left ventricular
global longitudinal strain (LVGLS) or global circumferential strain
(GCS) in patients with confirmed extra-cardiac sarcoidosis versus
healthy controls. Studies that exclusively included patients with
probable or definite CS were excluded. Continuous data were pooled as a
standard mean difference (SMD) between the sarcoidosis group and
controls. A random effect model was adopted in all analyses.
Heterogeneity was assessed using Q and I2 statistics.