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Small left atrial volume before ablation is a predictor of tachycardia-induced cardiomyopathy with atrial fibrillation
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  • Masahiro Nauchi,
  • Tsuyoshi Sakai,
  • Yuta Sugizaki,
  • Naohiko Sahara
Masahiro Nauchi
Saiseikai Yokohamashi Tobu Hospital

Corresponding Author:[email protected]

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Tsuyoshi Sakai
Saiseikai Yokohamashi Tobu Hospital
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Yuta Sugizaki
Saiseikai Yokohamashi Tobu Hospital
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Naohiko Sahara
Saiseikai Yokohamashi Tobu Hospital
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Abstract

Abstract Introduction: Tachycardia-induced cardiomyopathy (TCM) is a reversible cause of heart failure (HF) with impaired left ventricle (LV) function. However, the diagnosis is difficult before treatment or control of the arrhythmia for the first time. Methods: In this retrospective observational study, we observed 32 patients with paroxysmal or persistent atrial fibrillation (AF) who had impaired LV function without structural heart disease and who underwent catheter ablation. We defined impaired LV function as LV ejection fraction (LVEF) <50%. After ablation, the LVEF became <60% (Group 1; n = 11) or 60% (Group 2; n = 21). We compared the differences in baseline characteristics between the two groups. The patients in Group1 had no ischemic disease. A receiver operating curve (ROC) with area under the curve (AUC) was used to evaluate the prediction efficiency. Results: There were significant differences in left atrial (LA) volume (LAV) and LAV adjusted by body surface area (LAVI) measured by computed tomography (p < 0.05 for both). The AUCs were 0.810 and 0.823, respectively. The points at which sensitivity and specificity were maximum were 147 ml and 79. Small LAV and LAVI were predictors of LVEF improvement. Conclusion: Small LAV measured by computed tomography (CT) before ablation may be useful for diagnosis of TCM with AF.