Statistical analysis
Normality of the data was tested using the Shapiro-Wilk or Kolmogorov-Smirnov tests. Data are presented as median and inter-quartile range (IQR). Comparison between unrelated variables was conducted with Student’s t-test or Mann–Whitney U test, as appropriate. The chi-square and Fisher’s exact tests were used for comparison between categorical variables. Significance was accepted at p < 0.05. Statistical analyses were conducted using the IBM Statistical Package for the Social Sciences (IBM SPSS v.19; IBM Corporation Inc, Armonk, NY, USA).
The study protocol was approved by the ”Sheba Medical Center” Institutional Review Board (ID 4287-17-SMC) on the 28 of June 2017.