Introduction:
Cases of aplastic anemia (AA) and nephrotic syndrome (NS) are rare, and
most of them are considered to be the effects of chronic
graft-versus-host disease (GVHD) after allogenic hematopoietic stem cell
transplantation (HSCT)1).
Herein, we report a case of idiopathic AA with monosomy 7 that developed
NS during immunosuppressive treatment (IST) alone without HSCT. To the
best of our knowledge, this patient is the first case of NS presenting
during follow-up for AA without HSCT.
We discuss the possible contribution of monosomy 7 or the SAMD9and SAMD9L genes on chromosome 7 to the concomitant occurrence of
NS in AA.