Viral infection
The EBV and CMV infection status of patients and donors was analyzed. It
was observed that the PTLD group had an EBV infection rate of 95.8% and
a CMV infection rate of 20.8%, which differed from the EBV and CMV
infection rates of the control group, which were 48.9% and 22.9%,
respectively. A significant difference in EBV infection rates was
observed between the two groups. Statistical analysis demonstrated that
EBV infection is an important risk factor for PTLD (P<0.001).
No association was observed between CMV and PTLD in this study. The EBV
and CMV infection statuses of donors before transplantation were
classified as follows: donor-positive/recipient-negative,
donor-positive/recipient-positive, donor-negative/recipient-positive,
and donor-negative/recipient-negative. Statistical analysis showed that
the viral infection status of donors and recipients before surgery were
not statistically associated (P>0.05) (Table 3).