Conclusion
PTLD is a fatal complication that occurs after liver transplantation in
children. Baseline characteristics, laboratory indicators, and
transplantation-related indicators are not related to the occurrence of
PTLD. The results of this study suggest that EBV infection is an
independent risk factor for PTLD; thus, it is necessary to be aware of
the risk of PTLD when EBV is continuously replicating or the viral load
is high. In addition, tacrolimus is not a direct factor leading to the
occurrence of PTLD; however, a high serum tacrolimus concentration is
related to EBV infection. The degree of immunosuppression should be
reduced in children with continuously replicating EBV and a high
concentration of tacrolimus in the blood.