Conclusion
PTLD is a fatal complication that occurs after liver transplantation in children. Baseline characteristics, laboratory indicators, and transplantation-related indicators are not related to the occurrence of PTLD. The results of this study suggest that EBV infection is an independent risk factor for PTLD; thus, it is necessary to be aware of the risk of PTLD when EBV is continuously replicating or the viral load is high. In addition, tacrolimus is not a direct factor leading to the occurrence of PTLD; however, a high serum tacrolimus concentration is related to EBV infection. The degree of immunosuppression should be reduced in children with continuously replicating EBV and a high concentration of tacrolimus in the blood.