Study population
Participants with a partner in the reproductive age (18-45 year) were
recruited in our genetic counseling and prenatal diagnosis center before
pursuing genetic testing (mainly cell-free fetal DNA screening and
peripheral blood karyotype before pregnancy) at Women’s Hospital of
Nanjing Medical University from August 2019 to December 2019. Only
participants who were planning a pregnancy or undergoing pregnancy, were
living in China and had no mental or intellectual disabilities were
qualified to our questionnaire.