Parameter |
Estimate |
Standard Error |
Shrinkage |
Eta Bar P |
Fixed effects |
|
|
|
|
CLsys (L/h) |
0.705 |
0.0850 |
|
|
Vc (L) |
46.3 |
3.51 |
|
|
CLCRRT (L/h) |
1.91 |
0.0938 |
|
|
CLCr~CLsys |
0.635 |
0.306 |
|
|
Wt~Vd |
0.900 |
0.193 |
|
|
Random effects |
|
|
|
|
BSV CLsys (%CV) |
39.7 |
|
24.7% |
0.973 |
BSV Vc (%CV) |
33.0 |
|
14.9% |
0.791 |
BSV CLCRRT (%CV) |
12.4 |
|
59.4% |
0.934 |
Vc-CLsys(Correlation) |
0.349 |
|
|
|
Residual variability |
|
|
|
|
additive (mg/L) |
2.25 |
|
15.8% |
|
proportional (%CV) |
4.58 |
|
15.8% |
|