Logistic regression analysis
To analyze which factors influence submission of the PLPV to ClinVar,
multivariate logistic regression analysis was performed (IBM SPSS
statistics v.25, USA). Among the stepwise methods, the forward
likelihood ratio (LR) was selected. The independent variables
(covariates) were number of allele count, the ethnic population and the
genes. P < 0.05 indicated statistical significance.