Introduction
Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem-cell disorder that is characterized by hemolytic anemia, bone-marrow failure, and thrombosis.1 Thromboembolism in PNH is associated with poor prognosis and is a leading cause of death.2, 3 Making prompt diagnosis of thrombosis is important to help determine treatment for patients with PNH.4 However, making the diagnosis is sometimes challenging, partly because of caregivers’ unfamiliarity with its clinical manifestations. Despite the high frequency of intraabdominal thrombosis in PNH,2 reports of upper gastrointestinal manifestations of thrombotic complications are rare.5Here, we report a patient with PNH who developed gastric and duodenal lesions likely caused by transient mucosal ischemia due to PNH-related thrombosis. This case report was prepared according to the CARE Guidelines.6