Conclusions
The immune system is complex, dynamic and integrated in function so as
to fight against foreign substances (antigen) such as infection and
cancer. The results of the response are not only to eliminate the
foreign material through humeral (antibodies) and cell -mediated
mechanisms, but, to confer protection against future contact with the
antigen through memory B and T cell formation, and that forms the basis
of passive and active immunity (vaccinations). The improving knowledge
of the immune system has expanded the role of immunotherapy and vaccine
therapy in oncology. However, the immunodeficiency diseases, autoimmune
disease and the hypersensitivity reactions remain the major
short-comings of the immune response.
ACKNOWLEDGEMENT
We acknowledge the late Professor Anomah Ngu for his pioneering work on
immunotherapy and vaccination for HIV/ AIDS, and along with the late
Professor Beltus Bejanga remained the auhors’ mentors in the practice of
surgical oncology in Cameroon.
CONFLICT OF INTEREST
The authors declare no competing interests
AUTHOR CONTRIBUTIONS
EPW was the main author, EN contributed to literature search
CONSENT
Not applicable
DATA AVAILABILITY STATEMENT
The data that support the findings of this study are available on
request from the corresponding author. The data are not publicly
available due to privacy or ethical restriction.
ORCID
Elroy Patrick Weledji @https://orcid.
Org/0000.0002.0473.4883