Age, years |
86 [83-90] |
85 [81-87] |
82 [78-84] |
<0.001 |
0.087 |
<0.001 |
<0.001 |
Female sex |
14 (60.9%) |
116 (55.2%) |
32 (60.4%) |
0.727 |
|
|
|
Body mass index,kg/m2
|
25.9 [24.1-30.0] |
27.0
[24.2-30.2] |
28.0 [25.4 -30.5] |
0.321 |
|
|
|
Diabetes mellitus |
9 (40.9%) |
76 (36.2%) |
20 (37.7%) |
0.899 |
|
|
|
Hypertension |
20 (90.9%) |
183 (87.1%) |
46 (86.8%) |
0.871 |
|
|
|
Coronary artery disease |
14 (63.6%) |
100 (47.6%) |
21 (39.6%) |
0.164 |
|
|
|
Prior myocardial infarction |
3 (13.6%) |
33 (15.7%) |
11 (20.8%) |
0.630 |
|
|
|
Prior CABG |
2 (9.1%) |
17 (8.1%) |
4 (7.6%) |
0.933 |
|
|
|
Prior valvular surgery |
1 (4.6%) |
13 (6.3%) |
7 (13.5%) |
0.176 |
|
|
|
Atrial fibrillation |
12 (54.6%) |
80 (38.1%) |
21 (39.6%) |
0.339 |
|
|
|
Chronic obstructive pulmonary disease |
3 (13.6%) |
35 (16.7%) |
7
(13.2%) |
0.886 |
|
|
|
Previous stroke |
4 (18.2%) |
31 (14.8%) |
6 (11.3%) |
0.675 |
|
|
|
Peripheral vascular disease |
1 (4.6%) |
24 (11.4%) |
3 (5.7%) |
0.448 |
|
|
|
NYHA class III and IV |
20 (90.9%) |
155 (73.8%) |
32 (60.4%) |
0.020 |
0.076 |
0.009 |
0.054 |
Creatinine, mg/dL |
1.1 [0.9-1.4] |
1.0 [0.8-1.4] |
1.0
[0.8-1.2] |
0.659 |
|
|
|
Dialysis |
0 (0%) |
2 (1.0%) |
1 (1.9%) |
0.601 |
|
|
|
eGFR (ml/min) |
53.5 [43.1-66.6] |
62.8 [45.9-81.3] |
63.3
[49.9-81.9] |
0.457 |
|
|
|
Hemoglobin, g/dL |
12.5 [10.8-13.6] |
12.0 [10.8-13.1] |
12.3
[10.7-13.4] |
0.723 |
|
|
|
Logistic EuroSCORE |
18.4 [7.0-30.2] |
13.7 [8.4-20.6] |
10.0
[6.1-16.3] |
0.017 |
0.327 |
0.032 |
0.009 |
Frailty |
18 (78.3%) |
104 (49.5%) |
12 (22.6%) |
<0.001 |
0.001 |
<0.001 |
<0.001 |
STS score |
5.6 [3.9-12.1] |
5.4 [3.8-9.3] |
3.8 [2.8-6.0] |
0.002 |
0.713 |
0.038 |
<0.001 |
Echocardiographic Variables |
Echocardiographic
Variables |
Echocardiographic Variables |
Echocardiographic Variables |
Echocardiographic
Variables |
Echocardiographic Variables |
Echocardiographic Variables |
Echocardiographic
Variables |
Left ventricular ejection fraction, % |
55 [35-60] |
60 [52-66] |
60 [51-64] |
0.017 |
0.005 |
0.027 |
0.477 |
LVEF < 37.5% |
5 (26.3%) |
17 (8.1%) |
6 (11.3%) |
0.041 |
0.010 |
0.464 |
0.119 |
Maximum aortic gradient, mmHg |
62 [41.5-73] |
75 [62-90] |
77.6
[65-90] |
0.061 |
|
|
|
Mean aortic gradient, mmHg |
36.0 [24.0-48.5] |
43.2 [38.0-56.0] |
45.0 [41.0-54.2] |
0.073 |
|
|
|
Aortic valve area, cm2
|
0.8 [0.5-0.9] |
0.6
[0.5-0.8] |
0.7 [0.5-0.8] |
0.101 |
|
|
|
Grade III and IV Mitral regurgitation |
8 (42.1%) |
11 (5.5%) |
11
(22.0%) |
<0.001 |
<0.001 |
0.095 |
<0.001 |
Pulmonary hypertension |
6 (33.3%) |
69 (33.2%) |
13 (25.5%) |
0.566 |
|
|
|
PASP , mmHg |
34 [20-50] |
20 [20-45] |
39 [20-54] |
0.046 |
0.032 |
0.207 |
0.166 |