3.2. Cannabis consumption is related to worse attentional
performance
THC and its metabolites were measured in plasma and no THC was detected
in the control subjects or the cannabis users. The metabolites of THC
were not detected in the control subjects (n = 7), whereas among the
cannabis users (n = 6), plasma 11-OH-THC was found in 5 out of 6
subjects (mean concentration: 1.68 ± 0.55 ng/ml) and THC-COOH was
detected in all of these subjects (29.76 ± 6.15 ng/ml). The
neuropsychological assessment (Fig. 1) revealed that cannabis users
exhibited significantly worse attentional performance than healthy
controls in the spatial span direct recall test (p<0.01, Fig.
1A), consistent with previous data (Galindo et al., 2018). Furthermore,
a trend towards worse working memory was also detected in the spatial
span inverse recall test (p=0.068, Fig. 1D).