Figures captions
Figure 1 Study selection
Figure 2 Forest plot depicting pooled estimates for the association between mortality and the three level of renin-angiotensin system drug exposure (ACEIs/ARBs, ACEIs, ARBs)
Figure 3 Forest plot depicting pooled estimates for the association between Intensive Care Unit admission and the three level of renin-angiotensin system drug exposure (ACEIs/ARBs, ACEIs, ARBs)
Figure 4 Forest plot depicting pooled estimates for the association between the composite outcome of mortality/ Intensive Care admission and the three level of renin-angiotensin system drug exposure (ACEIs/ARBs, ACEIs, ARBs)
Figure 5 Forest plot depicting pooled estimates for the association between risk of acquiring COVID-19 infection and the three level of renin-angiotensin system drug exposure (ACEIs/ARBs, ACEIs, ARBs)
Figure 6 Forest plot depicting pooled estimates for the association between developing severe COVID-19 infection and the three level of renin-angiotensin system drug exposure (ACEIs/ARBs, ACEIs, ARBs)
Figure 7 Forest plot depicting pooled estimates for the association between hospitalisation and the three level of renin-angiotensin system drug exposure (ACEIs/ARBs, ACEIs, ARBs)
Figure 8 Forest plot depicting pooled estimate for the association between hospital discharge and ACEIs/ARBs use
Figure 9 Forest plot depicting pooled estimates for the association between use of ventilator and the three level of renin-angiotensin system drug exposure (ACEIs/ARBs, ACEIs, ARBs)
Figure 10 Forest plot depicting pooled estimates for the association between use of ventilator/Intensive Care Unit admission and the three level of renin-angiotensin system drug exposure (ACEIs/ARBs, ACEIs, ARBs)
Supplementary files’ captions and legends
Supplementary file 1. Search strategy in Medline (OVID)
Supplementary file 2. Forest plot depicting sub-group analyses pooled estimates for the association between mortality and ACEIs/ARBs use sub-grouped by A) country; B) methodological quality; C) peer-review status; and D) type of analyses (crude vs. adjusted)
Supplementary file 3. Forest plot depicting sub-group analyses pooled estimates for the association between Intensive Care Unit admission and ACEIs/ARBs use sub-grouped by A) country; B) methodological quality; C) peer-review status
Supplementary file 4. Forest plot depicting sub-group analyses pooled estimates for the association between the composite outcome of mortality/ Intensive Care admission and ACEIs/ARBs use sub-grouped by A) country; B) methodological quality; C) type of analyses (crude vs. adjusted)
Supplementary file 5A. Forest plot depicting sub-group analyses pooled estimates for the association between risk of acquiring COVID-19 infection and ACEIs/ARBs use sub-grouped by A) country; B) peer-review status; and C) type of analyses (crude vs. adjusted)
Supplementary 5B. Forest plot depicting sub-group analyses pooled estimates for the association between risk of acquiring COVID-19 infection and ACEIs use sub-grouped by A) country; B) methodological quality; C) peer-review status; and D) type of analyses (crude vs. adjusted)
Supplementary 5C. Forest plot depicting sub-group analyses pooled estimates for the association between risk of acquiring COVID-19 infection and ARBs use sub-grouped by A) methodological quality; B) peer-review status; and C) type of analyses (crude vs. adjusted)
Supplementary file 6. Forest plot depicting sub-group analyses pooled estimates for the association between developing severe COVID-19 infection and ACEIs/ARBs use sub-grouped by A) country; B) peer-review status; and C) type of analyses (crude vs. adjusted)
Supplementary file 7. Forest plot depicting sub-group analyses pooled estimates for the association between hospitalisation and ACEIs/ARBs use sub-grouped by A) country; B) methodological quality; C) peer-review status; and D) type of analyses (crude vs. adjusted)
Supplementary file 8. Forest plot depicting sub-group analyses pooled estimates for the association between hospital discharge and ACEIs/ARBs use sub-grouped by A) country; B) peer-review status
Supplementary file 9. Forest plot depicting sub-group analyses pooled estimates for the association between ventilator use and ACEIs/ARBs use sub-grouped by A) country; B) peer-review status