3.4 Cytokines in bone marrow
Significant increases of TNF-α, IFN-γ and IL-17 were observed in the
bone marrow of AA patients comparing with that in contral group with
11.20±35.20 vs . 2.80±0.70 pg/mL (P <0.0001),
35.00±7.80 vs . 13.00±5.80 pg/mL (P <0.0001) and
28.90±11.20 vs 2.60±0.30 pg/mL (P <0.0001),
respectively (Figure 4A). The levels of TNF-α, IFN-γ and IL-17 in
peripheral blood of AA group were also higher than that in the control
group, but there was no statistically significant difference (Figure
4B).