3.5  Decrease of LT-HSCs
Hematopoietic stem cell pools include LT-HSCs and ST-HSCs. In order to understand the status of subpopulations of HSCs in AA, we tested LT-HSCs and ST-HSCs. The results showed that both of them were significantly lower in bone marrow of children with AA than that in the control group(for LT-HSCs 1.13±0.82/100000 vs . 12.09±5.29/100000,P <0.0001; for ST-HSCs 2.79±1.75/100000 vs . 22.98±8.76/100000, P <0.0001)(Figure 5).